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IP-FCM Measures Physiologic Protein-Protein Interactions Modulated by Signal Transduction and Small-Molecule Drug Inhibition

Protein-protein interactions (PPI) mediate the formation of intermolecular networks that control biological signaling. For this reason, PPIs are of outstanding interest in pharmacology, as they display high specificity and may represent a vast pool of potentially druggable targets. However, the stud...

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Detalles Bibliográficos
Autores principales:	Smith, Stephen E. P., Bida, Anya T., Davis, Tessa R., Sicotte, Hugues, Patterson, Steven E., Gil, Diana, Schrum, Adam G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448684/ https://www.ncbi.nlm.nih.gov/pubmed/23029201 http://dx.doi.org/10.1371/journal.pone.0045722

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