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Lamin A/C Mutants Disturb Sumo1 Localization and Sumoylation in Vitro and in Vivo
A-type lamins A and C are nuclear intermediate filament proteins in which mutations have been implicated in multiple disease phenotypes commonly known as laminopathies. A few studies have implicated sumoylation in the regulation of A-type lamins. Sumoylation is a post-translational protein modificat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448699/ https://www.ncbi.nlm.nih.gov/pubmed/23029315 http://dx.doi.org/10.1371/journal.pone.0045918 |