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Glutamyl Phosphate Is an Activated Intermediate in Actin Crosslinking by Actin Crosslinking Domain (ACD) Toxin

Actin Crosslinking Domain (ACD) is produced by several life-threatening Gram-negative pathogenic bacteria as part of larger toxins and delivered into the cytoplasm of eukaryotic host cells via Type I or Type VI secretion systems. Upon delivery, ACD disrupts the actin cytoskeleton by catalyzing inter...

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Detalles Bibliográficos
Autores principales: Kudryashova, Elena, Kalda, Caitlin, Kudryashov, Dmitri S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448709/
https://www.ncbi.nlm.nih.gov/pubmed/23029200
http://dx.doi.org/10.1371/journal.pone.0045721