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Illuminating the Off-Pathway Nature of the Molten Globule Folding Intermediate of an α-β Parallel Protein
Partially folded protein species transiently form during folding of most proteins. Often, these species are molten globules, which may be on- or off-pathway to the native state. Molten globules are ensembles of interconverting protein conformers that have a substantial amount of secondary structure,...
Autores principales: | Lindhoud, Simon, Westphal, Adrie H., Borst, Jan Willem, van Mierlo, Carlo P. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448718/ https://www.ncbi.nlm.nih.gov/pubmed/23029219 http://dx.doi.org/10.1371/journal.pone.0045746 |
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