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APC/C(Cdh1) Targets Brain-Specific Kinase 2 (BRSK2) for Degradation via the Ubiquitin-Proteasome Pathway

Studies of brain-specific kinase 2 (BRSK2), an AMP-activated protein kinase (AMPK)-related kinase, and its homologs suggest that they are multifunctional regulators of cell-cycle progression. BRSK2, which contains a ubiquitin-associated (UBA) domain, is polyubiquitinated in cells. However, the regul...

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Detalles Bibliográficos
Autores principales:	Li, Ruwei, Wan, Bo, Zhou, Jun, Wang, Yingli, Luo, Ting, Gu, Xiuting, Chen, Fang, Yu, Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448725/ https://www.ncbi.nlm.nih.gov/pubmed/23029325 http://dx.doi.org/10.1371/journal.pone.0045932

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