Aquaporin-1 Translocation and Degradation Mediates the Water Transportation Mechanism of Acetazolamide

BACKGROUND: Diuretic agents are widely used on the treatment of water retention related diseases, among which acetazolamide (AZA) acts originally as a carbonic anhydrase (CA) inhibitor. Aquaporin-1 (AQP1) being located in renal proximal tubules is required for urine concentration. Previously our lab...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jianzhao, An, Yu, Gao, Junwei, Han, Jing, Pan, Xueyang, Pan, Yan, Tie, Lu, Li, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448731/
https://www.ncbi.nlm.nih.gov/pubmed/23029347
http://dx.doi.org/10.1371/journal.pone.0045976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448731/
https://www.ncbi.nlm.nih.gov/pubmed/23029347
http://dx.doi.org/10.1371/journal.pone.0045976

Ejemplares similares