Improvements in health-related quality of life after treatment with tocilizumab in patients with rheumatoid arthritis refractory to tumour necrosis factor inhibitors: results from the 24-week randomized controlled RADIATE study

Objective. To investigate the effect of tocilizumab on patient-reported outcomes (PROs) in RA patients with inadequate responses to TNF inhibitors (TNFis). Methods. In a Phase III randomized controlled trial, 489 patients received 4 or 8 mg/kg tocilizumab or placebo every 4 weeks plus MTX for 24 wee...

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Detalles Bibliográficos
Autores principales: Strand, Vibeke, Burmester, Gerd R., Ogale, Sarika, Devenport, Jenny, John, Ani, Emery, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448882/
https://www.ncbi.nlm.nih.gov/pubmed/22753773
http://dx.doi.org/10.1093/rheumatology/kes131

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