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Patched Knockout Mouse Models of Basal Cell Carcinoma

Basal cell carcinoma (BCC) is the most common human tumor. Mutations in the hedgehog (HH) receptor Patched (PTCH) are the main cause of BCC. Due to their high and increasing incidence, BCC are becoming all the more important for the health care system. Adequate animal models are required for the imp...

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Detalles Bibliográficos
Autores principales: Nitzki, Frauke, Becker, Marco, Frommhold, Anke, Schulz-Schaeffer, Walter, Hahn, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449132/
https://www.ncbi.nlm.nih.gov/pubmed/23024864
http://dx.doi.org/10.1155/2012/907543