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Prostaglandin E(2) and the Suppression of Phagocyte Innate Immune Responses in Different Organs

The local and systemic production of prostaglandin E(2) (PGE(2)) and its actions in phagocytes lead to immunosuppressive conditions. PGE(2) is produced at high levels during inflammation, and its suppressive effects are caused by the ligation of the E prostanoid receptors EP(2) and EP(4), which resu...

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Detalles Bibliográficos
Autores principales: Medeiros, Alexandra, Peres-Buzalaf, Camila, Fortino Verdan, Felipe, Serezani, C. Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449139/
https://www.ncbi.nlm.nih.gov/pubmed/23024463
http://dx.doi.org/10.1155/2012/327568