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Prostaglandin E(2) and the Suppression of Phagocyte Innate Immune Responses in Different Organs
The local and systemic production of prostaglandin E(2) (PGE(2)) and its actions in phagocytes lead to immunosuppressive conditions. PGE(2) is produced at high levels during inflammation, and its suppressive effects are caused by the ligation of the E prostanoid receptors EP(2) and EP(4), which resu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449139/ https://www.ncbi.nlm.nih.gov/pubmed/23024463 http://dx.doi.org/10.1155/2012/327568 |