Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report

ABSTRACT: Madelung’s disease or multiple symmetric lipomatosis (MSL) is a rare disorder of unknown etiology which typically presents symmetrically subcutaneous accumulation of non-encapsulated adipose tissue which slowly grows around the neck, upper part of the arms, pelvis, back and thigh. This dis...

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Detalles Bibliográficos
Autores principales: Borriello, Maddalena, Lucidi, Alessandro, Carbone, Arnaldo, Iannone, Vito, Ferrandina, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449177/
https://www.ncbi.nlm.nih.gov/pubmed/22937763
http://dx.doi.org/10.1186/1746-1596-7-116
Descripción
Sumario:ABSTRACT: Madelung’s disease or multiple symmetric lipomatosis (MSL) is a rare disorder of unknown etiology which typically presents symmetrically subcutaneous accumulation of non-encapsulated adipose tissue which slowly grows around the neck, upper part of the arms, pelvis, back and thigh. This disease is also frequently associated with hepatopathy, glucose intolerance, hyperuricemia, and malignant tumors of the upper airways. Nevertheless, only one description of malignant transformation of Madelung’s disease has been presented in literature. Here, we report a case of liposarcomatous transformation of Madelung’s disease in a 59-year-old Italian woman with a coincidental diagnosis of breast cancer. VIRTUAL SLIDE: The virtual slide for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/3480884087499351

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