Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report

ABSTRACT: Madelung’s disease or multiple symmetric lipomatosis (MSL) is a rare disorder of unknown etiology which typically presents symmetrically subcutaneous accumulation of non-encapsulated adipose tissue which slowly grows around the neck, upper part of the arms, pelvis, back and thigh. This dis...

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Autores principales: Borriello, Maddalena, Lucidi, Alessandro, Carbone, Arnaldo, Iannone, Vito, Ferrandina, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449177/
https://www.ncbi.nlm.nih.gov/pubmed/22937763
http://dx.doi.org/10.1186/1746-1596-7-116
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author Borriello, Maddalena
Lucidi, Alessandro
Carbone, Arnaldo
Iannone, Vito
Ferrandina, Gabriella
author_facet Borriello, Maddalena
Lucidi, Alessandro
Carbone, Arnaldo
Iannone, Vito
Ferrandina, Gabriella
author_sort Borriello, Maddalena
collection PubMed
description ABSTRACT: Madelung’s disease or multiple symmetric lipomatosis (MSL) is a rare disorder of unknown etiology which typically presents symmetrically subcutaneous accumulation of non-encapsulated adipose tissue which slowly grows around the neck, upper part of the arms, pelvis, back and thigh. This disease is also frequently associated with hepatopathy, glucose intolerance, hyperuricemia, and malignant tumors of the upper airways. Nevertheless, only one description of malignant transformation of Madelung’s disease has been presented in literature. Here, we report a case of liposarcomatous transformation of Madelung’s disease in a 59-year-old Italian woman with a coincidental diagnosis of breast cancer. VIRTUAL SLIDE: The virtual slide for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/3480884087499351
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spelling pubmed-34491772012-09-24 Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report Borriello, Maddalena Lucidi, Alessandro Carbone, Arnaldo Iannone, Vito Ferrandina, Gabriella Diagn Pathol Case Report ABSTRACT: Madelung’s disease or multiple symmetric lipomatosis (MSL) is a rare disorder of unknown etiology which typically presents symmetrically subcutaneous accumulation of non-encapsulated adipose tissue which slowly grows around the neck, upper part of the arms, pelvis, back and thigh. This disease is also frequently associated with hepatopathy, glucose intolerance, hyperuricemia, and malignant tumors of the upper airways. Nevertheless, only one description of malignant transformation of Madelung’s disease has been presented in literature. Here, we report a case of liposarcomatous transformation of Madelung’s disease in a 59-year-old Italian woman with a coincidental diagnosis of breast cancer. VIRTUAL SLIDE: The virtual slide for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/3480884087499351 BioMed Central 2012-09-01 /pmc/articles/PMC3449177/ /pubmed/22937763 http://dx.doi.org/10.1186/1746-1596-7-116 Text en Copyright ©2012 Borriello et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Borriello, Maddalena
Lucidi, Alessandro
Carbone, Arnaldo
Iannone, Vito
Ferrandina, Gabriella
Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
title Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
title_full Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
title_fullStr Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
title_full_unstemmed Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
title_short Malignant transformation of Madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
title_sort malignant transformation of madelung’s disease in a patient with a coincidental diagnosis of breast cancer: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449177/
https://www.ncbi.nlm.nih.gov/pubmed/22937763
http://dx.doi.org/10.1186/1746-1596-7-116
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