Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia

Schizophrenia is a highly heritable disorder with a polygenic pattern of inheritance and a population prevalence of ∼1%. Previous studies have implicated synaptic dysfunction in schizophrenia. We tested the accumulated association of genetic variants in expert-curated synaptic gene groups with schiz...

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Detalles Bibliográficos
Autores principales: Lips, E S, Cornelisse, L N, Toonen, R F, Min, J L, Hultman, C M, Holmans, P A, O'Donovan, M C, Purcell, S M, Smit, A B, Verhage, M, Sullivan, P F, Visscher, P M, Posthuma, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449234/
https://www.ncbi.nlm.nih.gov/pubmed/21931320
http://dx.doi.org/10.1038/mp.2011.117

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