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Prospective analysis of neutralising antibody titres in secondary non-responders under continuous treatment with a botulinumtoxin type A preparation free of complexing proteins—a single cohort 4-year follow-up study

OBJECTIVES: In long-term botulinum neurotoxin treatment, loss of therapeutic efficacy may occur due to neutralising antibody formation. Preliminary results with incobotulinumtoxinA, a preparation free of complexing/accessory proteins, have indicated a low antigenicity. We hypothesised that continuou...

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Detalles Bibliográficos
Autores principales:	Hefter, Harald, Hartmann, Christian, Kahlen, Ulrike, Moll, Marek, Bigalke, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Group 2012
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449271/ https://www.ncbi.nlm.nih.gov/pubmed/22864418 http://dx.doi.org/10.1136/bmjopen-2011-000646

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