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Primary Role of the Chromophore Bond Length Alternation in Reversible Photoconversion of Red Fluorescence Proteins

Rapid photobleaching of fluorescent proteins can limit their use in imaging applications. The underlying kinetics is multi-exponential and strongly depends on the local chromophore environment. The first, reversible, step may be attributed to a rotation around one of the two exocyclic C-C bonds brid...

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Detalles Bibliográficos
Autores principales: Drobizhev, Mikhail, Hughes, Thomas E., Stepanenko, Yuriy, Wnuk, Pawel, O'Donnell, Kieran, Scott, J. Nathan, Callis, Patrik R., Mikhaylov, Alexander, Dokken, Leslie, Rebane, Aleksander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449290/
https://www.ncbi.nlm.nih.gov/pubmed/23008753
http://dx.doi.org/10.1038/srep00688