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Dopamine D2 receptor-mediated Akt/PKB signalling: initiation by the D2S receptor and role in quinpirole-induced behavioural activation

The short and long isoforms of the dopamine D2 receptor (D2S and D2L respectively) are highly expressed in the striatum. Functional D2 receptors activate an intracellular signalling pathway that includes a cAMP-independent route involving Akt/GSK3 (glycogen synthase kinase 3). To investigate the Akt...

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Detalles Bibliográficos
Autores principales:	Chen, Han-Ting, Ruan, Nan-Yu, Chen, Jin-Chung, Lin, Tzu-Yung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Neurochemistry 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449306/ https://www.ncbi.nlm.nih.gov/pubmed/22909302 http://dx.doi.org/10.1042/AN20120013

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