Sinus Hypoplasia Precedes Sinus Infection in a Porcine Model of Cystic Fibrosis

OBJECTIVES/HYPOTHESIS: Chronic sinusitis is nearly universal in humans with cystic fibrosis (CF) and is accompanied by sinus hypoplasia (small sinuses). However, whether impaired sinus development is a primary feature of loss of the cystic fibrosis transmembrane conductance regulator (CFTR) or a sec...

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Detalles Bibliográficos
Autores principales: Chang, Eugene H, Pezzulo, Alejandro A, Meyerholz, David K, Potash, Andrea E, Wallen, Tanner J, Reznikov, Leah R, Sieren, Jessica C, Karp, Philip H, Ernst, Sarah, Moninger, Thomas O, Gansemer, Nicholas D, McCray, Paul B, Stoltz, David A, Welsh, Michael J, Zabner, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Allergy/Rhinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449319/
https://www.ncbi.nlm.nih.gov/pubmed/22711071
http://dx.doi.org/10.1002/lary.23392

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