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Interpretation of the Consequences of Mutations in Protein Kinases: Combined Use of Bioinformatics and Text Mining
Protein kinases play a crucial role in a plethora of significant physiological functions and a number of mutations in this superfamily have been reported in the literature to disrupt protein structure and/or function. Computational and experimental research aims to discover the mechanistic connectio...
Autores principales: | Izarzugaza, Jose M. G., Krallinger, Martin, Valencia, Alfonso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449330/ https://www.ncbi.nlm.nih.gov/pubmed/23055974 http://dx.doi.org/10.3389/fphys.2012.00323 |
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