Cargando…

Carbon distribution to toxic effect in toxin proteins

The role of hydrophobic force in biological function through the formation of several local macro-molecular structures is evident. Carbon is the element that contributes to biological function in living systems. We show that carbon distribution is related to protein activity using an example. The ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Akila, Kannaiyan, Kaliaperumal, Rajendran, Rajasekaran, Ekambaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449374/
https://www.ncbi.nlm.nih.gov/pubmed/23055617
http://dx.doi.org/10.6026/97320630008720
Descripción
Sumario:The role of hydrophobic force in biological function through the formation of several local macro-molecular structures is evident. Carbon is the element that contributes to biological function in living systems. We show that carbon distribution is related to protein activity using an example. The carbon distribution profile is foreseen to help undestand unfolded and misfolded regions of protein structures. The carbon distribution profile in a toxin protein that is found associated with the toxic shock syndrome is described in this study. The carbon profile provides insight to the association of specific residues responsible for toxicity.