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Carbon distribution to toxic effect in toxin proteins

The role of hydrophobic force in biological function through the formation of several local macro-molecular structures is evident. Carbon is the element that contributes to biological function in living systems. We show that carbon distribution is related to protein activity using an example. The ca...

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Detalles Bibliográficos
Autores principales: Akila, Kannaiyan, Kaliaperumal, Rajendran, Rajasekaran, Ekambaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449374/
https://www.ncbi.nlm.nih.gov/pubmed/23055617
http://dx.doi.org/10.6026/97320630008720
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author Akila, Kannaiyan
Kaliaperumal, Rajendran
Rajasekaran, Ekambaram
author_facet Akila, Kannaiyan
Kaliaperumal, Rajendran
Rajasekaran, Ekambaram
author_sort Akila, Kannaiyan
collection PubMed
description The role of hydrophobic force in biological function through the formation of several local macro-molecular structures is evident. Carbon is the element that contributes to biological function in living systems. We show that carbon distribution is related to protein activity using an example. The carbon distribution profile is foreseen to help undestand unfolded and misfolded regions of protein structures. The carbon distribution profile in a toxin protein that is found associated with the toxic shock syndrome is described in this study. The carbon profile provides insight to the association of specific residues responsible for toxicity.
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spelling pubmed-34493742012-10-09 Carbon distribution to toxic effect in toxin proteins Akila, Kannaiyan Kaliaperumal, Rajendran Rajasekaran, Ekambaram Bioinformation Hypothesis The role of hydrophobic force in biological function through the formation of several local macro-molecular structures is evident. Carbon is the element that contributes to biological function in living systems. We show that carbon distribution is related to protein activity using an example. The carbon distribution profile is foreseen to help undestand unfolded and misfolded regions of protein structures. The carbon distribution profile in a toxin protein that is found associated with the toxic shock syndrome is described in this study. The carbon profile provides insight to the association of specific residues responsible for toxicity. Biomedical Informatics 2012-08-03 /pmc/articles/PMC3449374/ /pubmed/23055617 http://dx.doi.org/10.6026/97320630008720 Text en © 2012 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
spellingShingle Hypothesis
Akila, Kannaiyan
Kaliaperumal, Rajendran
Rajasekaran, Ekambaram
Carbon distribution to toxic effect in toxin proteins
title Carbon distribution to toxic effect in toxin proteins
title_full Carbon distribution to toxic effect in toxin proteins
title_fullStr Carbon distribution to toxic effect in toxin proteins
title_full_unstemmed Carbon distribution to toxic effect in toxin proteins
title_short Carbon distribution to toxic effect in toxin proteins
title_sort carbon distribution to toxic effect in toxin proteins
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449374/
https://www.ncbi.nlm.nih.gov/pubmed/23055617
http://dx.doi.org/10.6026/97320630008720
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AT rajasekaranekambaram carbondistributiontotoxiceffectintoxinproteins