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Carbon distribution to toxic effect in toxin proteins
The role of hydrophobic force in biological function through the formation of several local macro-molecular structures is evident. Carbon is the element that contributes to biological function in living systems. We show that carbon distribution is related to protein activity using an example. The ca...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449374/ https://www.ncbi.nlm.nih.gov/pubmed/23055617 http://dx.doi.org/10.6026/97320630008720 |
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author | Akila, Kannaiyan Kaliaperumal, Rajendran Rajasekaran, Ekambaram |
author_facet | Akila, Kannaiyan Kaliaperumal, Rajendran Rajasekaran, Ekambaram |
author_sort | Akila, Kannaiyan |
collection | PubMed |
description | The role of hydrophobic force in biological function through the formation of several local macro-molecular structures is evident. Carbon is the element that contributes to biological function in living systems. We show that carbon distribution is related to protein activity using an example. The carbon distribution profile is foreseen to help undestand unfolded and misfolded regions of protein structures. The carbon distribution profile in a toxin protein that is found associated with the toxic shock syndrome is described in this study. The carbon profile provides insight to the association of specific residues responsible for toxicity. |
format | Online Article Text |
id | pubmed-3449374 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Biomedical Informatics |
record_format | MEDLINE/PubMed |
spelling | pubmed-34493742012-10-09 Carbon distribution to toxic effect in toxin proteins Akila, Kannaiyan Kaliaperumal, Rajendran Rajasekaran, Ekambaram Bioinformation Hypothesis The role of hydrophobic force in biological function through the formation of several local macro-molecular structures is evident. Carbon is the element that contributes to biological function in living systems. We show that carbon distribution is related to protein activity using an example. The carbon distribution profile is foreseen to help undestand unfolded and misfolded regions of protein structures. The carbon distribution profile in a toxin protein that is found associated with the toxic shock syndrome is described in this study. The carbon profile provides insight to the association of specific residues responsible for toxicity. Biomedical Informatics 2012-08-03 /pmc/articles/PMC3449374/ /pubmed/23055617 http://dx.doi.org/10.6026/97320630008720 Text en © 2012 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited. |
spellingShingle | Hypothesis Akila, Kannaiyan Kaliaperumal, Rajendran Rajasekaran, Ekambaram Carbon distribution to toxic effect in toxin proteins |
title | Carbon distribution to toxic effect in toxin proteins |
title_full | Carbon distribution to toxic effect in toxin proteins |
title_fullStr | Carbon distribution to toxic effect in toxin proteins |
title_full_unstemmed | Carbon distribution to toxic effect in toxin proteins |
title_short | Carbon distribution to toxic effect in toxin proteins |
title_sort | carbon distribution to toxic effect in toxin proteins |
topic | Hypothesis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449374/ https://www.ncbi.nlm.nih.gov/pubmed/23055617 http://dx.doi.org/10.6026/97320630008720 |
work_keys_str_mv | AT akilakannaiyan carbondistributiontotoxiceffectintoxinproteins AT kaliaperumalrajendran carbondistributiontotoxiceffectintoxinproteins AT rajasekaranekambaram carbondistributiontotoxiceffectintoxinproteins |