OrFin: A web tool for detection of putative orthologs

Identification of ortholog is one of the important tasks to understand a novel genome. It helps to assign functional annotations, from one organism to another organism. To identify the putative ortholog, Reciprocal Best BLAST hit (RBBH) method is known to be an efficient approach. OrFin makes use of...

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Detalles Bibliográficos
Autores principales: Midha, Mohit, Polavarapu, Raja, Meetei, Potshangbam Angamba, Krishnan, Hari, Mohareer, Krishnaveni, Vindal, Vaibhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Server
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449379/
https://www.ncbi.nlm.nih.gov/pubmed/23055622
http://dx.doi.org/10.6026/97320630008738
Descripción
Sumario:Identification of ortholog is one of the important tasks to understand a novel genome. It helps to assign functional annotations, from one organism to another organism. To identify the putative ortholog, Reciprocal Best BLAST hit (RBBH) method is known to be an efficient approach. OrFin makes use of the same approach to identify pair of orthologous proteins for a given set of sequences of two species. It is a user-friendly web tool which works with user defined parameters to search RBBHs. Results are produced in both html and text format. AVAILABILITY: This web tool is freely available at http://bifl.uohyd.ac.in/orfin

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