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Structure prediction of Bestrophin for the induced - fit docking of anthocyanins

Bestrophin, an integral membrane protein existing in basolateral region of the retina is a propitious target for drug discovery. Mutations in the Bestrophin protein cause Best Vitelliform Macular Dystrophy (BVMD) leading to retinal damages and loss of visual acuity. Owing to the lack of three dimens...

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Detalles Bibliográficos
Autores principales: Priya, Sathyan Sri Lavvanya, Devi, Ponnuswamy Renuka, Eganathan, Palanisami, Topno, Nishith Saurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449392/
https://www.ncbi.nlm.nih.gov/pubmed/23055624
http://dx.doi.org/10.6026/97320630008742