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Molecular characterization of novel trispecific ErbB-cMet-IGF1R antibodies and their antigen-binding properties
Therapeutic antibodies are well established drugs in diverse medical indications. Their success invigorates research on multi-specific antibodies in order to enhance drug efficacy by co-targeting of receptors and addressing key questions of emerging resistance mechanisms. Despite challenges in produ...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449402/ https://www.ncbi.nlm.nih.gov/pubmed/22936109 http://dx.doi.org/10.1093/protein/gzs048 |