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Antiepileptic drugs in the treatment of headache: neuroprotective effect or something else?

The hypothesis that cortical hyperexcitability may play an important role in the physiopathology of migraine has lead to the therapeutic use of antiepileptic drugs in headache prophylaxis. Cortical hyperexcitability is due to an imbalance between neuronal inhibition, mediated by gamma-aminobutyrric...

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Detalles Bibliográficos
Autores principales: Di Trapani, Girolamo, Mei, Daniele, Vollono, Catello, Capuano, Alessandro, Ferraro, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3451588/
http://dx.doi.org/10.1007/s10194-004-0124-3