Migraineurs with patent foramen ovale have larger right-to-left shunt despite similar atrial septal characteristics

The objective of the study was to assess differences in proportion of large right-to-left shunt (RLS) and atrial septal characteristics between migraineurs and non-migraineurs referred for transcatheter closure of patent foramen ovale (PF0). This retrospective study took place in a large metropolita...

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Detalles Bibliográficos
Autores principales: Jesurum, Jill T., Fuller, Cindy J., Velez, Carles A., Spencer, Merrill P., Krabill, Kimberly A., Likosky, William H., Gray, William A., Olsen, John V., Reisman, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2007
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3451677/
https://www.ncbi.nlm.nih.gov/pubmed/17901924
http://dx.doi.org/10.1007/s10194-007-0396-5
Descripción
Sumario:The objective of the study was to assess differences in proportion of large right-to-left shunt (RLS) and atrial septal characteristics between migraineurs and non-migraineurs referred for transcatheter closure of patent foramen ovale (PF0). This retrospective study took place in a large metropolitan medical centre. The patients were migraineurs with aura (n=52), migraineurs without aura (n=19) and non-migraineurs (n=149). RLS was evaluated before closure using bilateral power m-mode transcranial Doppler at rest and after calibrated, sustained Valsalva manoeuvre, and graded with a validated 0–5 scale. Intracardiac echocardiography was used to assess atrial septal characteristics. Migraineurs had a higher proportion of large RLS (Grade IV or V) than nonmigraineurs at rest and after calibrated Valsalva (rest, p=0.04; Valsalva, p=0.01). Atrial septal characteristics were similar between groups. Migraine is associated with larger RLS at rest and strain; however migraine status does not predict PFO characteristics.

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