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Genetics of cluster headache: an update
Up to a few years ago, cluster headache (CH) was not thought to be an inherited disorder. However, several recent studies have suggested that genetic factors play a role in the disease. Genetic epidemiological surveys have shown that first–degree relatives of CH patients are more likely to have CH t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3452030/ https://www.ncbi.nlm.nih.gov/pubmed/16362673 http://dx.doi.org/10.1007/s10194-005-0194-x |
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author | Pinessi, L. Rainero, I. Rivoiro, C. Rubino, E. Gallone, S. |
author_facet | Pinessi, L. Rainero, I. Rivoiro, C. Rubino, E. Gallone, S. |
author_sort | Pinessi, L. |
collection | PubMed |
description | Up to a few years ago, cluster headache (CH) was not thought to be an inherited disorder. However, several recent studies have suggested that genetic factors play a role in the disease. Genetic epidemiological surveys have shown that first–degree relatives of CH patients are more likely to have CH than the general population. CH has been reported in some concordant monozygotic twin pairs. At present, the type and the number of genes involved in the disease are still unclear. No mutation in the CACNA1A and NOS genes was found in CH patients. Recently, we have reported a significant association between the HCRTR2 gene and the disease. The purpose of this review is to describe recent advances in the genetics of CH. |
format | Online Article Text |
id | pubmed-3452030 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-34520302012-11-29 Genetics of cluster headache: an update Pinessi, L. Rainero, I. Rivoiro, C. Rubino, E. Gallone, S. J Headache Pain TACs AND CRANIAL NEURALAGIA Up to a few years ago, cluster headache (CH) was not thought to be an inherited disorder. However, several recent studies have suggested that genetic factors play a role in the disease. Genetic epidemiological surveys have shown that first–degree relatives of CH patients are more likely to have CH than the general population. CH has been reported in some concordant monozygotic twin pairs. At present, the type and the number of genes involved in the disease are still unclear. No mutation in the CACNA1A and NOS genes was found in CH patients. Recently, we have reported a significant association between the HCRTR2 gene and the disease. The purpose of this review is to describe recent advances in the genetics of CH. Springer-Verlag 2005-07-20 2005-09 /pmc/articles/PMC3452030/ /pubmed/16362673 http://dx.doi.org/10.1007/s10194-005-0194-x Text en © Springer-Verlag Italia 2005 |
spellingShingle | TACs AND CRANIAL NEURALAGIA Pinessi, L. Rainero, I. Rivoiro, C. Rubino, E. Gallone, S. Genetics of cluster headache: an update |
title | Genetics of cluster headache: an update |
title_full | Genetics of cluster headache: an update |
title_fullStr | Genetics of cluster headache: an update |
title_full_unstemmed | Genetics of cluster headache: an update |
title_short | Genetics of cluster headache: an update |
title_sort | genetics of cluster headache: an update |
topic | TACs AND CRANIAL NEURALAGIA |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3452030/ https://www.ncbi.nlm.nih.gov/pubmed/16362673 http://dx.doi.org/10.1007/s10194-005-0194-x |
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