Angiotensin II receptor antagonists against migraine in pregnancy: fatal outcome

A pregnant young woman with a severe migraine is prescribed candesartan, an angiotensin II type 1 receptor antagonist (AT II antagonists). This has a positive effect—except for severe maldevelopment of her fetus. There is an increase in the use of the fetotoxic drugs, AT II antagonists and angiotens...

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Detalles Bibliográficos
Autor principal: Haaland, Kirsti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2010
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3452282/
https://www.ncbi.nlm.nih.gov/pubmed/20063032
http://dx.doi.org/10.1007/s10194-009-0182-7
Descripción
Sumario:A pregnant young woman with a severe migraine is prescribed candesartan, an angiotensin II type 1 receptor antagonist (AT II antagonists). This has a positive effect—except for severe maldevelopment of her fetus. There is an increase in the use of the fetotoxic drugs, AT II antagonists and angiotensin-converting enzyme inhibitors, as prophylactic treatment of migraines, in addition to their use as hypertensives.

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