Cargando…
11,12-EET Stimulates the Association of BK Channel α and β(1) Subunits in Mitochondria to Induce Pulmonary Vasoconstriction
In the systemic circulation, 11,12-epoxyeicosatrienoic acid (11,12-EET) elicits nitric oxide (NO)- and prostacyclin-independent vascular relaxation, partially through the activation of large conductance Ca(2+)-activated potassium (BK) channels. However, in the lung 11,12-EET contributes to hypoxia-i...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454360/ https://www.ncbi.nlm.nih.gov/pubmed/23029390 http://dx.doi.org/10.1371/journal.pone.0046065 |