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Longitudinal Study of a Human Drug-Induced Model of Autoantibody to Cytoplasmic Rods/Rings following HCV Therapy with Ribavirin and Interferon-α

BACKGROUND: A novel pattern in the indirect immunofluorescence antinuclear antibody assay on HEp-2 cells (IIF-HEp-2) characterized by cytoplasmic rods and rings (RR) was reported in HCV patients, but stringent disease specificity studies and longitudinal analysis are lacking. We investigated the cli...

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Detalles Bibliográficos
Autores principales: Keppeke, Gerson Dierley, Nunes, Eunice, Ferraz, Maria Lucia Gomes, Silva, Eduardo Antônio Benedito, Granato, Celso, Chan, Edward K. L., Andrade, Luís Eduardo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454395/
https://www.ncbi.nlm.nih.gov/pubmed/23028980
http://dx.doi.org/10.1371/journal.pone.0045392