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Inhibition of Tcf-4 Induces Apoptosis and Enhances Chemosensitivity of Colon Cancer Cells

Aberrant activation of β-catenin/Tcf-4 signaling has been implicated in human carcinogenesis, including colorectal cancer. In this study, we compared the effects of Tcf-4 knockdown with β-catenin knockdown on cell proliferation, apoptosis, and chemosensitivity in SW480 and HCT116 colon cancer cells...

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Detalles Bibliográficos
Autores principales:	Xie, Jiang, Xiang, De-Bing, Wang, Hong, Zhao, Cong, Chen, Jie, Xiong, Feng, Li, Ting-Yu, Wang, Xiao-Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454396/ https://www.ncbi.nlm.nih.gov/pubmed/23029137 http://dx.doi.org/10.1371/journal.pone.0045617

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