Valproate Alters Dopamine Signaling in Association with Induction of Par-4 Protein Expression

Chromatin remodeling through histone modifications has emerged as a key mechanism in the pathophysiology of psychiatric disorders. Valproate (VPA), a first-line medication for bipolar disorder, is known to have histone deacetylase (HDAC) inhibitor activity, but the relationship between its efficacy...

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Detalles Bibliográficos
Autores principales: Lee, Saebom, Jeong, Jaehoon, Park, Young-Un, Kwak, Yongdo, Lee, Seol Ae, Lee, Haeryun, Son, Hyeon, Park, Sang Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454414/
https://www.ncbi.nlm.nih.gov/pubmed/23029138
http://dx.doi.org/10.1371/journal.pone.0045618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454414/
https://www.ncbi.nlm.nih.gov/pubmed/23029138
http://dx.doi.org/10.1371/journal.pone.0045618

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