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Live Attenuated S. Typhimurium Vaccine with Improved Safety in Immuno-Compromised Mice
Live attenuated vaccines are of great value for preventing infectious diseases. They represent a delicate compromise between sufficient colonization-mediated adaptive immunity and minimizing the risk for infection by the vaccine strain itself. Immune defects can predispose to vaccine strain infectio...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454430/ https://www.ncbi.nlm.nih.gov/pubmed/23029007 http://dx.doi.org/10.1371/journal.pone.0045433 |