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Importance of β-Catenin in glucose and energy homeostasis
In settings of increased insulin demand, failure to expand pancreatic β-cells mass leads to diabetes. Genome-wide scans of diabetic populations have uncovered several genes associated with susceptibility to type 2 diabetes and a number of them are part of the Wnt signaling. β-Catenin, a Wnt downstre...
Autores principales: | Elghazi, Lynda, Gould, Aaron P., Weiss, Aaron J., Barker, Daniel J., Callaghan, John, Opland, Darren, Myers, Martin, Cras-Méneur, Corentin, Bernal-Mizrachi, Ernesto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457035/ https://www.ncbi.nlm.nih.gov/pubmed/23012647 http://dx.doi.org/10.1038/srep00693 |
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