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Potential Role of Peptidylarginine Deiminase Enzymes and Protein Citrullination in Cancer Pathogenesis
The peptidylarginine deiminases (PADs) are a family of posttranslational modification enzymes that catalyze the conversion of positively charged protein-bound arginine and methylarginine residues to the uncharged, nonstandard amino acid citrulline. This enzymatic activity is referred to as citrullin...
Autores principales: | Mohanan, Sunish, Cherrington, Brian D., Horibata, Sachi, McElwee, John L., Thompson, Paul R., Coonrod, Scott A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457611/ https://www.ncbi.nlm.nih.gov/pubmed/23019525 http://dx.doi.org/10.1155/2012/895343 |
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