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The Fetal Origins of the Metabolic Syndrome: Can We Intervene?
Epidemiological studies have suggested that metabolic programming begins during fetal life and adverse events in utero are a critical factor in the etiology of chronic diseases and overall health. While the underlying molecular mechanisms linking impaired fetal development to these adult diseases ar...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457612/ https://www.ncbi.nlm.nih.gov/pubmed/23029616 http://dx.doi.org/10.1155/2012/482690 |
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author | Ma, Noelle Hardy, Daniel B. |
author_facet | Ma, Noelle Hardy, Daniel B. |
author_sort | Ma, Noelle |
collection | PubMed |
description | Epidemiological studies have suggested that metabolic programming begins during fetal life and adverse events in utero are a critical factor in the etiology of chronic diseases and overall health. While the underlying molecular mechanisms linking impaired fetal development to these adult diseases are being elucidated, little is known about how we can intervene early in life to diminish the incidence and severity of these long-term diseases. This paper highlights the latest clinical and pharmaceutical studies addressing how dietary intervention in fetal and neonatal life may be able to prevent aspects of the metabolic syndrome associated with IUGR pregnancies. |
format | Online Article Text |
id | pubmed-3457612 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-34576122012-10-01 The Fetal Origins of the Metabolic Syndrome: Can We Intervene? Ma, Noelle Hardy, Daniel B. J Pregnancy Review Article Epidemiological studies have suggested that metabolic programming begins during fetal life and adverse events in utero are a critical factor in the etiology of chronic diseases and overall health. While the underlying molecular mechanisms linking impaired fetal development to these adult diseases are being elucidated, little is known about how we can intervene early in life to diminish the incidence and severity of these long-term diseases. This paper highlights the latest clinical and pharmaceutical studies addressing how dietary intervention in fetal and neonatal life may be able to prevent aspects of the metabolic syndrome associated with IUGR pregnancies. Hindawi Publishing Corporation 2012 2012-09-17 /pmc/articles/PMC3457612/ /pubmed/23029616 http://dx.doi.org/10.1155/2012/482690 Text en Copyright © 2012 N. Ma and D. B. Hardy. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Ma, Noelle Hardy, Daniel B. The Fetal Origins of the Metabolic Syndrome: Can We Intervene? |
title | The Fetal Origins of the Metabolic Syndrome: Can We Intervene? |
title_full | The Fetal Origins of the Metabolic Syndrome: Can We Intervene? |
title_fullStr | The Fetal Origins of the Metabolic Syndrome: Can We Intervene? |
title_full_unstemmed | The Fetal Origins of the Metabolic Syndrome: Can We Intervene? |
title_short | The Fetal Origins of the Metabolic Syndrome: Can We Intervene? |
title_sort | fetal origins of the metabolic syndrome: can we intervene? |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457612/ https://www.ncbi.nlm.nih.gov/pubmed/23029616 http://dx.doi.org/10.1155/2012/482690 |
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