Nonintegral stoichiometry in CFTR gating revealed by a pore-lining mutation

Cystic fibrosis transmembrane conductance regulator (CFTR) is a unique member of the ATP-binding cassette (ABC) protein superfamily. Unlike most other ABC proteins that function as active transporters, CFTR is an ATP-gated chloride channel. The opening of CFTR’s gate is associated with ATP-induced d...

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Detalles Bibliográficos
Autores principales: Jih, Kang-Yang, Sohma, Yoshiro, Hwang, Tzyh-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457689/
https://www.ncbi.nlm.nih.gov/pubmed/22966014
http://dx.doi.org/10.1085/jgp.201210834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457689/
https://www.ncbi.nlm.nih.gov/pubmed/22966014
http://dx.doi.org/10.1085/jgp.201210834

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