Cargando…

Bcl6 expression specifies the T follicular helper cell program in vivo

T follicular helper cells (Tfh cells) play a pivotal role in germinal center reactions, which require B cell lymphoma 6 (Bcl6) transcription factor. To analyze their relationships with other effector T cell lineages and their stability in vivo, we developed and analyzed a new Bcl6 reporter mouse alo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xindong, Yan, Xiaowei, Zhong, Bo, Nurieva, Roza I., Wang, Aibo, Wang, Xiaohu, Martin-Orozco, Natalia, Wang, Yihong, Chang, Seon Hee, Esplugues, Enric, Flavell, Richard A., Tian, Qiang, Dong, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457730/ https://www.ncbi.nlm.nih.gov/pubmed/22987803 http://dx.doi.org/10.1084/jem.20120219

Ejemplares similares

Transcription factor Achaete-Scute homologue 2 initiates T follicular helper cell development
por: Liu, Xindong, et al.
Publicado: (2014)

Follicular helper T cells progressively differentiate to regulate the germinal center response
por: Weinstein, Jason S., et al.
Publicado: (2016)

Insights Into the Molecular Mechanisms of T Follicular Helper-Mediated Immunity and Pathology
por: Qin, Lei, et al.
Publicado: (2018)

Batf is important for IL-4 expression in T follicular helper cells
por: Sahoo, Anupama, et al.
Publicado: (2015)

Transient T-bet expression functionally specifies a distinct T follicular helper subset
por: Fang, Difeng, et al.
Publicado: (2018)

Bcl-6-directed follicular helper T cells promote vascular inflammatory injury in diabetic retinopathy
por: Liu, Yan, et al.
Publicado: (2020)

Follicular regulatory T (Tfr) cells with dual Foxp3 and Bcl6 expression suppress germinal center reactions
por: Chung, Yeonseok, et al.
Publicado: (2011)

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19
por: Kaneko, Naoki, et al.
Publicado: (2020)

The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6
por: Stauss, Dennis, et al.
Publicado: (2016)

Early Growth Response Genes 2 and 3 Regulate the Expression of Bcl6 and Differentiation of T Follicular Helper Cells
por: Ogbe, Ane, et al.
Publicado: (2015)

LEF-1 and TCF-1 orchestrate T follicular helper cell differentiation by regulating differentiation circuits upstream of Bcl6
por: Choi, Youn Soo, et al.
Publicado: (2015)

Bcl-6 is the nexus transcription factor of T follicular helper cells (T(FH)) via repressor-of-repressor circuits
por: Choi, Jinyong, et al.
Publicado: (2020)

UHRF1 downregulation promotes T follicular helper cell differentiation by increasing BCL6 expression in SLE
por: Liu, Limin, et al.
Publicado: (2021)

Life of T Follicular Helper Cells
por: Suh, Woong-Kyung
Publicado: (2015)

Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus
por: Donnarumma, Tiziano, et al.
Publicado: (2016)

Effect of follicular helper T cells on the pathogenesis of asthma
por: Ma, Xiaojuan, et al.
Publicado: (2017)

Follicular Helper T Cells (Tfh) and IL-21 Involvement in the Pathogenesis of Bullous Pemphigoid
por: Li, Qiuju, et al.
Publicado: (2013)

T follicular helper cells in patients with acute schistosomiasis
por: Zhang, Yumei, et al.
Publicado: (2016)

Interleukin-1 in the Response of Follicular Helper and Follicular Regulatory T Cells
por: Ritvo, Paul-Gydéon, et al.
Publicado: (2019)

T follicular helper cells and T follicular regulatory cells in autoimmune diseases
por: Qi, Jingjing, et al.
Publicado: (2023)

Multi-Source Pathways of T Follicular Helper Cell Differentiation
por: Ma, Xiaoxue, et al.
Publicado: (2021)

Dependence on Bcl6 and Blimp1 drive distinct differentiation of murine memory and follicular helper CD4(+) T cells
por: Ciucci, Thomas, et al.
Publicado: (2021)

Regulation of T follicular helper cells by ICOS
por: Hutloff, Andreas
Publicado: (2015)

Follicular helper T cell in immunity and autoimmunity
por: Mesquita, D., et al.
Publicado: (2016)

T Follicular Helper Cells in Autoimmune Disorders
por: Gensous, Noémie, et al.
Publicado: (2018)

Primary cutaneous T‐follicular helper lymphoma
por: Fenu, Elena M., et al.
Publicado: (2023)

T Follicular Regulatory Cell Suppression of T Follicular Helper Cell Function Is Context-Dependent in vitro
por: Lopez-Ocasio, Maria, et al.
Publicado: (2020)

Negative regulation of IL-17-mediated signaling and inflammation by ubiquitin-specific protease 25
por: Zhong, Bo, et al.
Publicado: (2012)

T follicular helper cells: a potential therapeutic target in follicular lymphoma
por: Ochando, Jordi, et al.
Publicado: (2017)

T follicular helper and T follicular regulatory cells have different TCR specificity
por: Maceiras, Ana Raquel, et al.
Publicado: (2017)

Helios Is Associated with CD4 T Cells Differentiating to T Helper 2 and Follicular Helper T Cells In Vivo Independently of Foxp3 Expression
por: Serre, Karine, et al.
Publicado: (2011)

Corrigendum: Multi-Source Pathways of T Follicular Helper Cell Differentiation
por: Ma, Xiaoxue, et al.
Publicado: (2021)

Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases
por: Yoshitomi, Hiroyuki, et al.
Publicado: (2020)

Follicular helper T cells are required for systemic autoimmunity
por: Linterman, Michelle A., et al.
Publicado: (2009)

Follicular helper T Cells and the B cells they help
por: Poholek, A, et al.
Publicado: (2012)

The origins, function, and regulation of T follicular helper cells
por: Ma, Cindy S., et al.
Publicado: (2012)

MicroRNAs, T follicular helper cells and inflammaging
por: Hawkes, Jason E., et al.
Publicado: (2015)

Memory T Follicular Helper CD4 T Cells
por: Hale, J. Scott, et al.
Publicado: (2015)

Insights into the Role of Follicular Helper T Cells in Autoimmunity
por: Park, Hong-Jai, et al.
Publicado: (2014)

Regulation of T Follicular Helper Cells in Islet Autoimmunity
por: Serr, Isabelle, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_egn1euuqga8so05m48qpvcv25r