Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts

Although tumor surveillance by T and B lymphocytes is well studied, the role of innate immune cells, in particular macrophages, is less clear. Moreover, the existence of subclonal genetic and functional diversity in some human cancers such as leukemia underscores the importance of defining tumor sur...

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Detalles Bibliográficos
Autores principales: Theocharides, Alexandre P.A., Jin, Liqing, Cheng, Po-Yan, Prasolava, Tatiana K., Malko, Andrei V., Ho, Jenny M., Poeppl, Armando G., van Rooijen, Nico, Minden, Mark D., Danska, Jayne S., Dick, John E., Wang, Jean C.Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457732/
https://www.ncbi.nlm.nih.gov/pubmed/22945919
http://dx.doi.org/10.1084/jem.20120502

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