Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult

BACKGROUND: Transgenic mice expressing disease-associated proteins have become standard tools for studying human neurological disorders. Transgenes are often expressed using promoters chosen to drive continuous high-level expression throughout life rather than temporal and spatial fidelity to the en...

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Detalles Bibliográficos
Autores principales: Rodgers, Shaefali P, Born, Heather A, Das, Pritam, Jankowsky, Joanna L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457908/
https://www.ncbi.nlm.nih.gov/pubmed/22709352
http://dx.doi.org/10.1186/1750-1326-7-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457908/
https://www.ncbi.nlm.nih.gov/pubmed/22709352
http://dx.doi.org/10.1186/1750-1326-7-28

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