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Inhibition of poly(ADP-ribose) Polymerase Interferes with Trypanosoma cruzi Infection and Proliferation of the Parasite

Poly(ADP-ribosylation) is a post-translational covalent modification of proteins catalyzed by a family of enzymes termed poly(ADP-ribose) polymerases (PARPs). In the human genome, 17 different genes have been identified that encode members of the PARP superfamily. Poly (ADP-ribose) metabolism plays...

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Detalles Bibliográficos
Autores principales:	Vilchez Larrea, Salomé C., Haikarainen, Teemu, Narwal, Mohit, Schlesinger, Mariana, Venkannagari, Harikanth, Flawiá, Mirtha M., Villamil, Silvia H. Fernández, Lehtiö, Lari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457943/ https://www.ncbi.nlm.nih.gov/pubmed/23049934 http://dx.doi.org/10.1371/journal.pone.0046063

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