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Low-Dose Dextromethorphan, a NADPH Oxidase Inhibitor, Reduces Blood Pressure and Enhances Vascular Protection in Experimental Hypertension
BACKGROUND: Vascular oxidative stress may be increased with age and aggravate endothelial dysfunction and vascular injury in hypertension. This study aimed to investigate the effects of dextromethorphan (DM), a NADPH oxidase inhibitor, either alone or in combination treatment, on blood pressure (BP)...
Autores principales: | Wu, Tao-Cheng, Chao, Chih-Yu, Lin, Shing-Jong, Chen, Jaw-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457948/ https://www.ncbi.nlm.nih.gov/pubmed/23049937 http://dx.doi.org/10.1371/journal.pone.0046067 |
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