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Preferential Colonization of Metastases by Oncolytic Vaccinia Virus Strain GLV-1h68 in a Human PC-3 Prostate Cancer Model in Nude Mice

Recently, we showed that the oncolytic vaccinia virus GLV-1h68 has a significant therapeutic potential in treating lymph node metastases of human PC-3 prostate carcinoma in tumor xenografts. In this study, underlying mechanisms of the virus-mediated metastases reduction were analyzed. Immunohistoche...

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Detalles Bibliográficos
Autores principales: Donat, Ulrike, Weibel, Stephanie, Hess, Michael, Stritzker, Jochen, Härtl, Barbara, Sturm, Julia B., Chen, Nanhai G., Gentschev, Ivaylo, Szalay, Aladar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457966/
https://www.ncbi.nlm.nih.gov/pubmed/23049897
http://dx.doi.org/10.1371/journal.pone.0045942