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Preferential Colonization of Metastases by Oncolytic Vaccinia Virus Strain GLV-1h68 in a Human PC-3 Prostate Cancer Model in Nude Mice
Recently, we showed that the oncolytic vaccinia virus GLV-1h68 has a significant therapeutic potential in treating lymph node metastases of human PC-3 prostate carcinoma in tumor xenografts. In this study, underlying mechanisms of the virus-mediated metastases reduction were analyzed. Immunohistoche...
Autores principales: | Donat, Ulrike, Weibel, Stephanie, Hess, Michael, Stritzker, Jochen, Härtl, Barbara, Sturm, Julia B., Chen, Nanhai G., Gentschev, Ivaylo, Szalay, Aladar A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457966/ https://www.ncbi.nlm.nih.gov/pubmed/23049897 http://dx.doi.org/10.1371/journal.pone.0045942 |
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