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Resting-State Network Disruption and APOE Genotype in Alzheimer's Disease: A lagged Functional Connectivity Study
BACKGROUND: The apolipoprotein E epsilon 4 (APOE-4) is associated with a genetic vulnerability to Alzheimer's disease (AD) and with AD-related abnormalities in cortical rhythms. However, it is unclear whether APOE-4 is linked to a specific pattern of intrinsic functional disintegration of the b...
Autores principales: | Canuet, Leonides, Tellado, Ivan, Couceiro, Veronica, Fraile, Carmen, Fernandez-Novoa, Lucia, Ishii, Ryouhei, Takeda, Masatoshi, Cacabelos, Ramon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457973/ https://www.ncbi.nlm.nih.gov/pubmed/23050006 http://dx.doi.org/10.1371/journal.pone.0046289 |
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