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c-Abl Inhibition Delays Motor Neuron Degeneration in the G93A Mouse, an Animal Model of Amyotrophic Lateral Sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive death of motor neurons. Although the pathogenesis of ALS remains unclear, several cellular processes are known to be involved, including apoptosis. A previous study revealed the apoptosi...

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Detalles Bibliográficos
Autores principales:	Katsumata, Ryu, Ishigaki, Shinsuke, Katsuno, Masahisa, Kawai, Kaori, Sone, Jun, Huang, Zhe, Adachi, Hiroaki, Tanaka, Fumiaki, Urano, Fumihiko, Sobue, Gen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458026/ https://www.ncbi.nlm.nih.gov/pubmed/23049975 http://dx.doi.org/10.1371/journal.pone.0046185

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