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A Soluble Form of CTLA-4 Is Present in Paediatric Patients with Acute Lymphoblastic Leukaemia and Correlates with CD1d(+) Expression

CTLA-4 is a key factor in regulating and maintaining self tolerance, providing a negative signal to the T cell and thus limiting immune responses. Several polymorphisms within the CTLA-4 gene have been associated with an increased risk of developing autoimmune diseases and, very recently, with susce...

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Detalles Bibliográficos
Autores principales:	Simone, Rita, Tenca, Claudya, Fais, Franco, Luciani, Matteo, De Rossi, Giulio, Pesce, Giampaola, Bagnasco, Marcello, Saverino, Daniele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458033/ https://www.ncbi.nlm.nih.gov/pubmed/23049754 http://dx.doi.org/10.1371/journal.pone.0044654

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