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Tie2-Dependent Neovascularization of the Ischemic Hindlimb Is Mediated by Angiopoietin-2

The angiopoietins (ANGPT) are ligands for the endothelial cell (EC) receptor tyrosine kinase, Tie2. Angpt-1 is a Tie2 agonist that promotes vascular maturation and stabilization, whereas Angpt-2 is a partial agonist/antagonist involved in the initiation of postnatal angiogenesis. Therefore, we hypot...

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Detalles Bibliográficos
Autores principales:	Lekas, Michael, Lekas, Poli, Mei, Shirley H. J., Deng, Yupu, Dumont, Daniel J., Stewart, Duncan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458045/ https://www.ncbi.nlm.nih.gov/pubmed/23049737 http://dx.doi.org/10.1371/journal.pone.0043568

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