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Single Amino Acid Substitutions in the Chemotactic Sequence of Urokinase Receptor Modulate Cell Migration and Invasion

The receptor for urokinase-type plasminogen activator (uPAR) plays an important role in controlling cell migration. uPAR binds urokinase and vitronectin extracellular ligands, and signals in complex with transmembrane receptors such as Formyl-peptide Receptors (FPR)s and integrins. Previous work fro...

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Detalles Bibliográficos
Autores principales: Bifulco, Katia, Longanesi-Cattani, Immacolata, Franco, Paola, Pavone, Vincenzo, Mugione, Pietro, Di Carluccio, Gioconda, Masucci, Maria Teresa, Arra, Claudio, Pirozzi, Giuseppe, Stoppelli, Maria Patrizia, Carriero, Maria Vincenza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458052/
https://www.ncbi.nlm.nih.gov/pubmed/23049759
http://dx.doi.org/10.1371/journal.pone.0044806