Cargando…

Single Amino Acid Substitutions in the Chemotactic Sequence of Urokinase Receptor Modulate Cell Migration and Invasion

The receptor for urokinase-type plasminogen activator (uPAR) plays an important role in controlling cell migration. uPAR binds urokinase and vitronectin extracellular ligands, and signals in complex with transmembrane receptors such as Formyl-peptide Receptors (FPR)s and integrins. Previous work fro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bifulco, Katia, Longanesi-Cattani, Immacolata, Franco, Paola, Pavone, Vincenzo, Mugione, Pietro, Di Carluccio, Gioconda, Masucci, Maria Teresa, Arra, Claudio, Pirozzi, Giuseppe, Stoppelli, Maria Patrizia, Carriero, Maria Vincenza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458052/ https://www.ncbi.nlm.nih.gov/pubmed/23049759 http://dx.doi.org/10.1371/journal.pone.0044806

Ejemplares similares

Involvement of the Soluble Urokinase Receptor in Chondrosarcoma Cell Mobilization
por: Bifulco, Katia, et al.
Publicado: (2011)

Urokinase receptor promotes ovarian cancer cell dissemination through its 84-95 sequence
por: Bifulco, Katia, et al.
Publicado: (2014)

Therapeutic Strategies Targeting Urokinase and Its Receptor in Cancer
por: Masucci, Maria Teresa, et al.
Publicado: (2022)

Cyclization of the Urokinase Receptor-Derived Ser-Arg-Ser-Arg-Tyr Peptide Generates a Potent Inhibitor of Trans-Endothelial Migration of Monocytes
por: Yousif, Ali Munaim, et al.
Publicado: (2015)

Emerging Targeted Therapeutic Strategies to Overcome Imatinib Resistance of Gastrointestinal Stromal Tumors
por: Masucci, Maria Teresa, et al.
Publicado: (2023)

Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas
por: Carriero, Maria Vincenza, et al.
Publicado: (2017)

The urokinase receptor-derived cyclic peptide [SRSRY] suppresses neovascularization and intravasation of osteosarcoma and chondrosarcoma cells
por: Ingangi, Vincenzo, et al.
Publicado: (2016)

Modulation of Cellular Function by the Urokinase Receptor Signalling: A Mechanistic View
por: Alfano, Daniela, et al.
Publicado: (2022)

Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells
por: Ragone, Concetta, et al.
Publicado: (2017)

Inhibiting Monocyte Recruitment to Prevent the Pro-Tumoral Activity of Tumor-Associated Macrophages in Chondrosarcoma
por: Minopoli, Michele, et al.
Publicado: (2020)

MicroRNAs as Key Players in Melanoma Cell Resistance to MAPK and Immune Checkpoint Inhibitors
por: Motti, Maria Letizia, et al.
Publicado: (2020)

Tumor Associated Neutrophils. Their Role in Tumorigenesis, Metastasis, Prognosis and Therapy
por: Masucci, Maria Teresa, et al.
Publicado: (2019)

The Emerging Role of Neutrophil Extracellular Traps (NETs) in Tumor Progression and Metastasis
por: Masucci, Maria Teresa, et al.
Publicado: (2020)

Structure-function relationship of an Urokinase Receptor-derived peptide which inhibits the Formyl Peptide Receptor type 1 activity
por: Minopoli, Michele, et al.
Publicado: (2019)

Phosphorylation of Human Pro-Urokinase on Ser(138/303) Impairs Its Receptor-dependent Ability to Promote Myelomonocytic Adherence and Motility
por: Franco, Paola, et al.
Publicado: (1997)

Breast Tumor Cell Invasion and Pro-Invasive Activity of Cancer-Associated Fibroblasts Co-Targeted by Novel Urokinase-Derived Decapeptides
por: Belli, Stefania, et al.
Publicado: (2020)

Proteomic analysis of zoledronic-acid resistant prostate cancer cells unveils novel pathways characterizing an invasive phenotype
por: Milone, Maria Rita, et al.
Publicado: (2014)

Targeting the Formyl Peptide Receptor type 1 to prevent the adhesion of ovarian cancer cells onto mesothelium and subsequent invasion
por: Minopoli, Michele, et al.
Publicado: (2019)

Inhibiting the urokinase‐type plasminogen activator receptor system recovers STZ‐induced diabetic nephropathy
por: Dal Monte, Massimo, et al.
Publicado: (2018)

Decoding the chemotactic signal
por: Thomas, Monica A., et al.
Publicado: (2018)

Herbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase
por: Lin, Yuli, et al.
Publicado: (2013)

Structural determinants of the eosinophil: chemotactic activity of the acidic tetrapeptides of eosinophil chemotactic factor of anaphylaxis
Publicado: (1976)

In silico docking of urokinase plasminogen activator and integrins
por: Degryse, Bernard, et al.
Publicado: (2008)

Chemotactic response of monocytes to thrombin
Publicado: (1983)

Chemotactic smoothing of collective migration
por: Bhattacharjee, Tapomoy, et al.
Publicado: (2022)

Pectobacterium brasiliense 1692 Chemotactic Responses and the Role of Methyl-Accepting Chemotactic Proteins in Ecological Fitness
por: Tanui, Collins Kipngetich, et al.
Publicado: (2021)

Effect of ABT-888 on the apoptosis, motility and invasiveness of BRAFi-resistant melanoma cells
por: Fratangelo, Federica, et al.
Publicado: (2018)

Controversial Role of Kisspeptins/KiSS-1R Signaling System in Tumor Development
por: Fratangelo, Federica, et al.
Publicado: (2018)

miR-204 Targeting of Ankrd13A Controls Both Mesenchymal Neural Crest and Lens Cell Migration
por: Avellino, Raffaella, et al.
Publicado: (2013)

Exogenous Urokinase Inhibits Proteasomal Degradation of Its Cognate Urokinase Plasminogen Activator Receptor
por: Zhu, Ran, et al.
Publicado: (2022)

AN EOSINOPHIL LEUKOCYTE CHEMOTACTIC FACTOR OF ANAPHYLAXIS
por: Kay, A. B., et al.
Publicado: (1971)

The selective eosinophil chemotactic activity of histamine
Publicado: (1975)

Sensory adaptation of leukocytes to chemotactic peptides
Publicado: (1979)

Selective neutrophil desensitization to chemotactic factors
Publicado: (1979)

Chemotactic Signaling by Single-Chain Chemoreceptors
por: Mowery, Patricia, et al.
Publicado: (2015)

Optimal chemotactic responses in stochastic environments
por: Godány, Martin, et al.
Publicado: (2017)

Chemotactic self-caging in active emulsions
por: Hokmabad, Babak Vajdi, et al.
Publicado: (2022)

Survivin is an essential mediator of arthritis interacting with urokinase signalling
por: Baran, Marcin, et al.
Publicado: (2009)

Coordinated Regulation of Mesenchymal Stem Cell Migration by Various Chemotactic Stimuli
por: Nam, Donghyun, et al.
Publicado: (2020)

Urokinase and macrophages in tumour angiogenesis.
por: Hildenbrand, R., et al.
Publicado: (1995)

Cannot write session to /tmp/vufind_sessions/sess_a4kuraaqehqhlqce2d6ghgfn9c