Protein Stability and Dynamics Modulation: The Case of Human Frataxin

Frataxin (FXN) is an α/β protein that plays an essential role in iron homeostasis. Apparently, the function of human FXN (hFXN) depends on the cooperative formation of crucial interactions between helix α1, helix α2, and the C-terminal region (CTR) of the protein. In this work we quantitatively expl...

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Detalles Bibliográficos
Autores principales: Roman, Ernesto A., Faraj, Santiago E., Gallo, Mariana, Salvay, Andres G., Ferreiro, Diego U., Santos, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458073/
https://www.ncbi.nlm.nih.gov/pubmed/23049850
http://dx.doi.org/10.1371/journal.pone.0045743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458073/
https://www.ncbi.nlm.nih.gov/pubmed/23049850
http://dx.doi.org/10.1371/journal.pone.0045743

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