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Proteome Analysis Identified the PPARγ Ligand 15d-PGJ2 as a Novel Drug Inhibiting Melanoma Progression and Interfering with Tumor-Stroma Interaction
Peroxisome proliferator-activated receptors (PPARs) have been originally thought to be restricted to lipid metabolism or glucose homeostasis. Recently, evidence is growing that PPARγ ligands have inhibitory effects on tumor growth. To shed light on the potential therapeutic effects on melanoma we te...
Autores principales: | Paulitschke, Verena, Gruber, Silke, Hofstätter, Elisabeth, Haudek-Prinz, Verena, Klepeisz, Philipp, Schicher, Nikolaus, Jonak, Constanze, Petzelbauer, Peter, Pehamberger, Hubert, Gerner, Christopher, Kunstfeld, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458105/ https://www.ncbi.nlm.nih.gov/pubmed/23049949 http://dx.doi.org/10.1371/journal.pone.0046103 |
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